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Symbol Name ID |
Tnfsf4
tumor necrosis factor (ligand) superfamily, member 4 MGI:104511 |
| * | Aspects of the system are reported to show a normal phenotype. |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
decreased T cell proliferation |
increased T cell proliferation |
abnormal T cell subpopulation ratio |
increased CD4-positive, alpha-beta T cell number |
increased regulatory T cell number |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal dendritic cell antigen presentation |
decreased susceptibility to type IV hypersensitivity reaction |
increased susceptibility to type IV hypersensitivity reaction |
abnormal cell-mediated immunity |
abnormal cytokine secretion |
decreased interferon-gamma secretion |
increased interleukin-13 secretion |
decreased interleukin-2 secretion |
decreased interleukin-4 secretion |
decreased susceptibility to autoimmune diabetes |
lung inflammation |
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| Availability | Mouse Genotype | ||||||||||||||||||
| Tnfsf4tm1Shr/Tnfsf4tm1Shr | * | ||||||||||||||||||
| Tnfsf4tm1Sug/Tnfsf4tm1Sug | |||||||||||||||||||
| Tg(Actb-Tnfsf4)1Nish/0 | |||||||||||||||||||
| Tg(Lck-Tnfsf4)1Nish/0 | ! | ! | ! | ! | ! | ||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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